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KMID : 1240020180220030192
International Neurourology Journal
2018 Volume.22 No. 3 p.192 ~ p.199
Factors Influencing Lower Urinary Tract Symptoms in Advanced Cancer Patients With Chemotherapy-Induced Peripheral Neuropathy
Cho Ok-Hee

Yoo Yang-Sook
Kim Joon-Chul
Park Ran-Hee
Hwang Kyung-Hye
Abstract
Purpose: This study aimed to investigate the severity of lower urinary tract symptoms (LUTS) and to identify factors that influenced LUTS in advanced cancer patients with chemotherapy-induced peripheral neuropathy (CIPN).

Methods: This cross-sectional study included a total of 158 advanced cancer patients with CIPN. A structured questionnaire including the International Prostate Symptom Score and the Functional Assessment of Cancer Therapy/Gynecology Oncology Group/Neurotoxicity scale was used. Data were analyzed using the Pearson correlation coefficient and multiple regression analysis.

Results: Nocturia was the most prevalent LUTS. A positive relationship was found between CIPN symptoms and LUTS. The duration of cancer diagnosis and the severity of CIPN were key factors that influenced LUTS.

Conclusions: The severity of CIPN symptoms was the most important predictor of LUTS. Nurses¡¯ care for advanced cancer patients should incorporate a comprehensive health assessment, which includes a history of treatment and physical neuropathic symptoms, for any patient complaining of CIPN symptoms.
KEYWORD
Neoplasm metastasis, Patients, Peripheral neuropathy, Lower urinary tract symptomsy
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